T-SPOT®.TB Test

The T-SPOT.TB test is an in vitro blood test for the diagnosis of active and latent TB. The test detects the immune response of T cells that have been stimulated by Mycobacterium tuberculosis (MTB) antigens by utilizing MTB-specific antigens (ESAT-6 and CFP 10) that are absent from BCG strains and most non-tuberculosis mycobacteria.   

The T-SPOT.TB test addresses the unique requirements of all groups tested for TB:  

The T-SPOT.TB test was designed to deliver highly accurate results:

• Results unaffected by BCG vaccination and most common non-tuberculosis mycobacteria
• Highly Sensitive

Benefits of the T-SPOT.TB test are:

• Can be used for all high risk groups for TB screening 
• Utilizes standard blood collection tubes
• No special phlebotomy training required 
• "One and Done": no second visit required to read test results
• Cost-effective

Interpretation of Results:

• Interferon gamma is captured and presented as spots from T cells sensitized to Mycobacterium tuberculosis antigens
• Results are interpreted by subtracting the spot count in the negative (NIL) control from the spot count in Panels A and B